5-(4-Fluorobenzylidene)rhodanine

CAS: 402-93-7

Ref. 3D-FF80282

Informação sobre produto

• Nome: 5-(4-Fluorobenzylidene)rhodanine
• Sinónimos: (5E)-5-(4-Fluorobenzylidene)-2-thioxo-1,3-thiazolidin-4-one, 4(5H)-thiazolone, 5-[(4-fluorophenyl)methylene]-2-mercapto-, (5E)-, 4-thiazolidinone, 5-[(4-fluorophenyl)methylene]-2-thioxo-, (5E)-, Rhodanine, 5- (p-fluorobenzylidene)-, Rhodanine, 5-(4-fluorobenzylidene)-

Descrição

5-(4-Fluorobenzylidene)rhodanine is an isomeric compound that belongs to the class of carbonyl compounds. It has a dipolar nature and hydrogen bonds with other molecules. 5-(4-Fluorobenzylidene)rhodanine is synthesized by reacting 4-fluorobenzaldehyde with a hydrazine derivative in the presence of an acid catalyst, such as hydrochloric acid. This process produces two diastereomers, which can be separated using column chromatography. 5-(4-Fluorobenzylidene)rhodanine has antitubercular activity against Mycobacterium tuberculosis, including multidrug-resistant strains. It also has been shown to have anti-inflammatory properties that are due to its ability to inhibit prostaglandin synthesis.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 239.29 g/mol
• Fórmula: C₁₀H₆FNOS₂
• Pureza: Min. 95%
• InChI: InChI=1S/C10H6FNOS2/c11-7-3-1-6(2-4-7)5-8-9(13)12-10(14)15-8/h1-5H,(H,12,13,14)/b8-5+
• Chave InChI: InChIKey=BQOQSIQMDZUHKF-VMPITWQZSA-N
• SMILES: O=C1NC(=S)S/C1=C/c1ccc(F)cc1