1-(4-Fluorosulfonylbenzoyl)Oxy-2,5-Dioxopyrrolidine-3-Sulfonic Acid

CAS: 142439-47-2

Ref. 3D-FF98329

Informação sobre produto

• Nome: 1-(4-Fluorosulfonylbenzoyl)Oxy-2,5-Dioxopyrrolidine-3-Sulfonic Acid
• Sinónimos: 1-((4-(Fluorosulfonyl)benzoyl)oxy)-2,5-dioxo-3-pyrrolidinesulfonic acid, Ssfsb, 3-Pyrrolidinesulfonic acid, 1-((4-(fluorosulfonyl)benzoyl)oxy)-2,5-dioxo-, 1-({[4-(Fluorosulfonyl)Phenyl]Carbonyl}Oxy)-2,5-Dioxopyrrolidine-3-Sulfonic Acid

Descrição

The 1-(4-fluorosulfonylbenzoyl)oxy-2,5-dioxopyrrolidine-3-sulfonic acid (1-FSB) is a potent inhibitor of receptor tyrosine kinases such as EGFR and PDGFR. It inhibits the growth of epidermal cells by binding to EGFR, which may lead to skin cancer. The 1-FSB is an aminoacylase inhibitor that binds to the active site of tryptic proteases, inhibiting their function and leading to increased synthesis of epidermal growth factor (EGF). The 1-FSB has been shown to inhibit the growth of carcinoma cells in vitro and in vivo.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 381.31 g/mol
• Fórmula: C₁₁H₈FNO₉S₂
• Pureza: Min. 95%
• InChI: InChI=1S/C11H8FNO9S2/c12-23(17,18)7-3-1-6(2-4-7)11(16)22-13-9(14)5-8(10(13)15)24(19,20)21/h1-4,8H,5H2,(H,19,20,21)
• Chave InChI: InChIKey=ATTYFJLOQAZRCE-UHFFFAOYSA-N
• SMILES: O=C(ON1C(=O)CC(S(=O)(=O)O)C1=O)c1ccc(S(=O)(=O)F)cc1