10-Gingerol

CAS: 23513-15-7

Ref. 3D-FG09323

Informação sobre produto

• Nome: 10-Gingerol
• Sinónimos: (S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone, (+)-(S)-[10]-Gingerol, (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone, (5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one, (5S)-[10]-Gingerol, 3-Tetradecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-, 3-Tetradecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)-

Descrição

10-Gingerol is a phenolic compound that is found in the ginger plant. It has been shown to inhibit tumor growth and induce apoptosis in mouse and human endothelial cells. 10-Gingerol also inhibits the growth of mycobacterium tuberculosis by binding to its ribosomes, inhibiting protein synthesis. The anti-inflammatory effect of gingerols may be due to inhibition of the enzyme synthase kinase-3β (SKK3β), which regulates inflammatory responses. 10-gingerol has also been shown to inhibit platelet aggregation, with an IC50 value of 4.1 µM, likely through inhibition of cyclooxygenases or thromboxane synthetase activity. 10-Gingerol can be detected using a reversed phase HPLC method with an IEC6 cell model as well as a UV detector at 254 nm.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 350.24571
• Fórmula: C₂₁H₃₄O₄
• Pureza: Min. 95%
• Cor/forma: White To Off-White Solid
• InChI: InChI=1S/C21H34O4/c1-3-4-5-6-7-8-9-10-18(22)16-19(23)13-11-17-12-14-20(24)21(15-17)25-2/h12,14-15,18,22,24H,3-11,13,16H2,1-2H3/t18-/m0/s1
• Chave InChI: InChIKey=AIULWNKTYPZYAN-SFHVURJKSA-N
• SMILES: CCCCCCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1