Z-Gly-Leu-OH

CAS: 1421-69-8

Ref. 3D-FG111476

Informação sobre produto

• Nome: Z-Gly-Leu-OH
• Sinónimos: <span class="text-smallcaps">L</span>-Leucine, N-[(phenylmethoxy)carbonyl]glycyl-, <span class="text-smallcaps">L</span>-Leucine, N-[N-[(phenylmethoxy)carbonyl]glycyl]-, Leucine, N-(N-carboxyglycyl)-, N-benzyl ester, Leucine, N-(N-carboxyglycyl)-, N-benzyl ester, <span class="text-smallcaps">L</span>-, N-(Benzyloxycarbonyl)glycyl-<span class="text-smallcaps">L</span>-leucine, N-(Benzyloxycarbonyl)glycylleucine, N-Benzyloxycarbonylglycyl-L-leucine, N-Carbobenzoxyglycyl-<span class="text-smallcaps">L</span>-leucine, N-[(Phenylmethoxy)carbonyl]glycyl-<span class="text-smallcaps">L</span>-leucine, N-[(benzyloxy)carbonyl]glycyl-D-leucine, N-[(benzyloxy)carbonyl]glycylleucine, NSC 89638
• CAS: 1421-69-8

Descrição

Z-Gly-Leu-OH is a synthetic peptide that is used as a substrate for proteases. It contains the amino acid sequence Gly-Leu-OH and has been shown to inhibit serine proteases with irreversible inhibition. Z-Gly-Leu-OH inhibits protease activity by binding to the enzyme's active site, which prevents it from catalyzing reactions and stabilizing the product of the reaction. The substrate can be cleaved by a protease in two ways: (1) hydrolysis of the amide bond between Gly and Leu or (2) protonation of the amide bond between Gly and Leu followed by elimination of water. These reactions are reversible because they are dependent on pH. In order to measure enzyme activity using this substrate, it must be conjugated with a fluorescent dye so that fluorescence can be detected following cleavage.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 322.36 g/mol
• Fórmula: C₁₆H₂₂N₂O₅
• Pureza: Min. 95%