GS 9620

CAS: 1228585-88-3

Ref. 3D-FG146405

Informação sobre produto

• Nome: GS 9620
• Sinónimos: Vesatolimod
• CAS: 1228585-88-3

Descrição

GS 9620 is a prodrug that is converted to its active form, GS-9669, in the liver. The conversion of GS-9620 to GS-9669 is catalyzed by cytochrome P450 (CYP) family 3A4 and 2D6 enzymes. GS-9620 has been shown to reduce hepatic steatosis in mice with chronic viral hepatitis and can be used as an adjunct therapy with other antiretroviral drugs for HIV infection. GS-9620 has antiviral activity against a variety of viruses including HIV, hepatitis B virus, and hepatitis C virus. It also inhibits the activation of toll-like receptors that are involved in inflammation.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 410.51 g/mol
• Fórmula: C₂₂H₃₀N₆O₂
• Pureza: Min. 95%
• Cor/forma: Solid
• InChI: InChI=1S/C22H30N6O2/c1-2-3-11-30-22-25-20(23)19-21(26-22)28(15-18(29)24-19)14-17-8-6-7-16(12-17)13-27-9-4-5-10-27/h6-8,12H,2-5,9-11,13-15H2,1H3,(H,24,29)(H2,23,25,26)
• Chave InChI: InChIKey=VFOKSTCIRGDTBR-UHFFFAOYSA-N
• SMILES: CCCCOc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2