Gly-Sar-OH

CAS: 29816-01-1

Ref. 3D-FG49318

Informação sobre produto

• Nome: Gly-Sar-OH
• Sinónimos: Glycyl-sarcosine, 2-(2-Amino-N-methylacetamido)acetic acid, 2-[(2-Aminoacetyl)-methylamino]acetic acid, Gly-Sar, Glycine, N-glycyl-N-methyl-, Glycine, glycyl-N-methyl-, Glycylsarcosine, H-Gly-Sar-OH, NSC 206288, Sarcosine, N-glycyl-, glycyl-N-methylglycine
• CAS: 29816-01-1

Descrição

Gly-Sar-OH is a peptidomimetic that inhibits the efflux function of P-glycoprotein (P-gp). It has been shown to inhibit the uptake of digoxin and other drugs into cells. Gly-Sar-OH inhibits the transport of drugs by P-gp, which is a membrane transporter protein found in certain tissues and organs, such as the intestines, brain, and kidney. It also inhibits the uptake of digoxin and other drugs into cells. The matrix effect is due to glycosaminoglycans binding to drug molecules to form a complex before being transported across cell membranes. Gly-Sar-OH also has been shown to be an inhibitor of energy metabolism in tumor cells.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 146.14 g/mol
• Fórmula: C₅H₁₀N₂O₃
• Pureza: Min. 95%
• InChI: InChI=1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)
• Chave InChI: InChIKey=VYAMLSCELQQRAE-UHFFFAOYSA-N
• SMILES: CN(CC(=O)O)C(=O)CN