Hirudin (54-65) (sulfated)

CAS: 109528-49-6

Ref. 3D-FH110098

Informação sobre produto

• Nome: Hirudin (54-65) (sulfated)
• Sinónimos: H-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
• CAS: 109528-49-6

Descrição

Hirudin is a protein that functions as an anticoagulant by binding to the active site of thrombin, preventing it from converting fibrinogen into fibrin. It has a high affinity for the thrombin receptor and can be modified in various ways. Hirudin's most common modification is sulfation, which enhances its anticoagulant activity. Hirudin is a proteolytic enzyme that can be synthesized using solid-phase chemistry. Its biological function is to inhibit blood coagulation by inhibiting the conversion of fibrinogen to fibrin. Hirudin binds to thrombin, preventing it from converting fibrinogen into fibrin and thus inhibits coagulation. It also prevents clot formation by inhibiting platelet aggregation, which may result from interactions with other proteins such as prothrombin and factor VIII.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 1,548.58 g/mol
• Fórmula: C₆₆H₉₃N₁₃O₂₈S
• Pureza: Min. 95%