Hydroxy bosentan
CAS: 253688-60-7
Ref. 3D-FH23919
| 1mg | Descontinuado | ||
| 2mg | Descontinuado | ||
| 5mg | Descontinuado | ||
| 10mg | Descontinuado | ||
| 25mg | Descontinuado |
Informação sobre produto
Nome:
Hydroxy bosentan
Sinónimos:
- 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamideRo 48-8634Ro 48-5033
Descrição:
Hydroxy bosentan is a drug used for the treatment of pulmonary arterial hypertension and is often used in combination with other drugs. Hydroxy bosentan binds to the alpha-1 adrenergic receptor and blocks the binding of sildenafil, which is a phosphodiesterase type 5 (PDE5) inhibitor. This leads to an increase in cGMP levels and improved blood flow in the lungs. Hydroxy bosentan has been shown to be safe for use in pediatric populations, although it can have adverse effects on liver function. Hydroxy bosentan's pharmacokinetic properties are dependent on renal function, as they are eliminated through the kidneys. There is also evidence that hydroxy bosentan may be taken up by red blood cells, leading to increased plasma concentrations.
Aviso:
Os nossos productos estão destinados exclusivamente para uso em laboratório. Para qualquer outra aplicação, por favor entre em contacto.
Marca:
Biosynth
Armazenamento a longo prazo:
Notas:
Propriedades químicas
Peso molecular:
567.61 g/mol
Fórmula:
C27H29N5O7S
Pureza:
Min. 95%
Cor/forma:
White To Off-White Solid
MDL:
Ponto de fusão:
Ponto de ebulição:
Ponto de inflamação:
Densidade:
Concentração:
EINECS:
Merck:
Código HS:
