Hydroxy itraconazole

CAS: 112559-91-8

Ref. 3D-FH24024

Informação sobre produto

• Nome: Hydroxy itraconazole
• Sinónimos: 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1 ,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl] phenyl]-2 ,4-dihydro-2-(2-hydroxy-1-methylpropyl)-3H-1,2,4-triazol-3-one, 3H-1,2,4-Triazol-3-one, 4-4-4-4-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethoxyphenyl-1-piperazinylphenyl-2,4-dihydro-2-(2-hydroxy-1-methylpropyl)-, 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(2-hydroxy-1-methylpropyl)-3H-1,2,4-triazol-3-one, R 63373, 4-{4-[4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2-(3-hydroxybutan-2-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, 4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2-(2-hydroxy-1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Descrição

Hydroxyitraconazole is an antifungal drug that inhibits the synthesis of ergosterol, a component of fungal cell membranes. It has been shown to be effective against a number of human pathogens, including Aspergillus fumigatus and Candida albicans. Hydroxyitraconazole has a broad spectrum of activity against a range of microbial organisms and is active against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus. The pharmacokinetic properties of hydroxyitraconazole have been studied in humans with normal renal function. A pharmacokinetic study was conducted to determine the effects on serum cortisol concentrations after administration of hydroxyitraconazole. This drug is not metabolized by cytochrome P450 enzymes and it does not induce or inhibit other drug metabolism pathways. Hydroxyitraconazole also has no significant interaction with other drugs or food products

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 721.63 g/mol
• Fórmula: C₃₅H₃₈Cl₂N₈O₅
• Pureza: Min. 98 Area-%
• Cor/forma: Powder