4-Hydroxy-7-methoxycoumarin
CAS: 17575-15-4
Ref. 3D-FH24294
| 1g | Descontinuado | ||
| 2g | Descontinuado | ||
| 5g | Descontinuado | ||
| 10g | Descontinuado | ||
| 25g | Descontinuado |
Informação sobre produto
Nome:
4-Hydroxy-7-methoxycoumarin
Sinónimos:
- 7-Methoxy-4-hydroxycoumarin4-Hydroxy-7-methoxy-2H-1-benzopyran-2-one4-Hydroxy-herniarin
- 2H-1-Benzopyran-2-One, 4-Hydroxy-7-Methoxy-
- 7-Methoxy-4-Hydroxycoumarin
- Aurora Ka-3735
- 4-Hydroxy-7-Methoxycoumarin 97%
- 2-hydroxy-7-methoxy-4H-chromen-4-one
- 4-hydroxy-7-methoxy-2H-chromen-2-one
Descrição:
4-Hydroxy-7-methoxycoumarin (4OHM) is a fluorescent compound that is used as a pharmacological probe. It has been shown to activate the mitogen-activated protein kinase (MAPK) cascade, which is involved in regulating cell growth and proliferation. 4OHM also induces the release of interleukin (IL)-1β and prostaglandin E2 from human monocytes, which are involved in inflammatory diseases. 4OHM has also been shown to induce necrosis in cells with low levels of extracellular ATP by inhibiting the enzyme phosphatase 2A. This inhibition leads to increased levels of intracellular calcium ions and reactive oxygen species, leading to necrosis through activation of proteases such as calpain.
Aviso:
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Marca:
Biosynth
Armazenamento a longo prazo:
Notas:
Propriedades químicas
Peso molecular:
192.17 g/mol
Fórmula:
C10H8O4
Pureza:
Min. 95%
InChI:
InChI=1S/C10H8O4/c1-13-6-2-3-7-8(11)5-10(12)14-9(7)4-6/h2-5,11H,1H3
Chave InChI:
InChIKey=MJBHLQMPKBMZSF-UHFFFAOYSA-N
SMILES:
COc1ccc2c(O)cc(=O)oc2c1
MDL:
Ponto de fusão:
Ponto de ebulição:
Ponto de inflamação:
Densidade:
Concentração:
EINECS:
Merck:
Código HS:
