N-Hydroxymaleimide
CAS: 4814-74-8
Ref. 3D-FH24382
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Informação sobre produto
- N-Hydroxymaleamine1-Hydroxy-2,5-dihydro-1H-pyrrole-2,5-dione
- 1-Hydroxy-2,5-dihydro-1H-pyrrole-2,5-dione
- 1-Hydroxypyrrole-2,5-dione
- 1H-Pyrrole-2,5-dione, 1-hydroxy-
- Maleimide, N-hydroxy-
N-Hydroxymaleimide is a reactive amide that is used as an oxidation catalyst in the synthesis of monoclonal antibodies. It is also used in the preparation of conjugates for immunological assays. N-Hydroxymaleimide is typically synthesized by liquid phase methods, which are more efficient than solid phase methods. The reaction proceeds through the dehydration of an amine with a primary or secondary alcohol to form an amide. This process is irreversible and must be carried out under mild conditions to avoid side reactions with functional groups on the reactants. N-Hydroxymaleimide can be purified by gel chromatography methods before use, but it cannot be stored for long periods because it reacts with water, trifluoroacetic acid, and many other substances.
Propriedades químicas
Consulta técnica sobre: 3D-FH24382 N-Hydroxymaleimide
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