5-Hydroxyquinolin-2(1H)-one
CAS: 31570-97-5
Ref. 3D-FH24497
1g | 483,00 € | ||
50mg | 136,00 € | ||
100mg | 151,00 € | ||
250mg | 215,00 € | ||
500mg | 343,00 € |
Informação sobre produto
- 5-Hydroxy-2(1H)-quinolone5-Hydroxycarbostyril5-Hydroxyquinolin-2(1H)-one
5-Hydroxyquinolin-2(1H)-one is a chalcone that can be synthesized from 2,5-dihydroxybenzaldehyde and quinoline. It is a bacteriostatic agent that inhibits bacterial growth by binding to the 50S ribosomal subunit, blocking the formation of an antibiotic-substrate complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. 5-Hydroxyquinolin-2(1H)-one has shown activity against methicillin resistant Staphylococcus aureus (MRSA) and methicillin resistant Enterococcus faecium. 5-Hydroxyquinolin-2(1H)-one also represses the expression of DNA topoisomerase II genes, which may be associated with its inhibitory effects on bacterial growth.
Propriedades químicas
Consulta técnica sobre: 3D-FH24497 5-Hydroxyquinolin-2(1H)-one
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