Isoquinoline-1,5-diol
CAS: 5154-02-9
Ref. 3D-FI13066
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Informação sobre produto
- 1,5-Dihydroxyisoquinoline5- Hydroxy- 1(2H)- isoquinolinone
- -Hydroxy-1(2H)-Isoquinoline
- 1(2H)-isoquinolinone, 5-hydroxy-
- 1,5-Dihydroxyisoquinoline
- 1,5-Iqd
- 1,5-Isoquinolinediol
- 5-Hydroxy-1(2H)-isoquinolinone
- 5-Hydroxyisocarbostyril
- NSC 65585
Isoquinoline-1,5-diol is an activated compound that is believed to exert its biological activity by binding to the mitochondrial membrane potential. It has been shown to activate the cardiac K+ channels in vivo and in vitro models. Isoquinoline-1,5-diol also increases the glomerular filtration rate and prevents cervical cancer cell growth in vitro. This agent may be used as a therapeutic agent for myocardial infarcts, which are caused by a reduction of cardiac output secondary to coronary artery disease. Isoquinoline-1,5-diol activates adenylate cyclase and increases 3'-5'adenosine monophosphate (AMP) levels. The enzyme dopamine synthetase is inhibited by this drug. The drug may also have clinical relevance as a treatment for Parkinson's disease due to its ability to inhibit tyrosine hydroxylase activity.
Propriedades químicas
Consulta técnica sobre: 3D-FI13066 Isoquinoline-1,5-diol
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