4-Iodo suberoylanilide hydroxamic acid
CAS: 1219807-87-0
Ref. 3D-FI24597
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Informação sobre produto
- N1-Hydroxy-N8-(4-iodophenyl)octanediamide4-Iodo-SAHA
4-Iodo suberoylanilide hydroxamic acid is a small molecule that inhibits the growth of cancer cells by binding to and inhibiting the activity of mitochondrial cytochrome c oxidase. This inhibition of the mitochondrial respiratory chain leads to oxidative stress, which triggers apoptosis. 4-Iodo suberoylanilide hydroxamic acid has been shown to be effective in treating cancers that are resistant to chemotherapy, such as leukemia and lymphoma. The drug also has a low toxicity profile. 4-Iodo suberoylanilide hydroxamic acid binds to the active site on cytochrome c oxidase in a number of ways, including steric hindrance, hydrogen bonding, and electrostatic interactions. This binding prevents the heme group from binding with oxygen, blocking electron transport and leading to cell death.
Propriedades químicas
Consulta técnica sobre: 3D-FI24597 4-Iodo suberoylanilide hydroxamic acid
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