Kenpaullone

CAS: 142273-20-9

Ref. 3D-FK24755

Informação sobre produto

• Nome: Kenpaullone
• Sinónimos: 9-Bromo-7,12-dihydro-indolo[3,2-d][1]-benzazepin-6(5H)-one9-Bromopaullone, 8-Bromo-7,12-Dihydro-Indolo[3,2-D][1]-Benzazepin-6(5H)-One, 9-Bromo-7,12-Dihydro-Indolo[3,2-D][1]Benzazepin-6(5H)-One, 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one, NSC 664704, 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one, 9-Bromopaullone, Indolo[3,2-d][1]benzazepin-6(5H)-one, 9-bromo-7,12-dihydro-, Nsc-664704

Descrição

Inhibitor of glycogen synthase 3 (GSK-3) and cyclin-dependent kinases CDK1, CDK2 and CDK5. Kenpaullone can substitute transcription factor Klf4 in reprogramming of fibroblast to induced pluripotent stem cells when using the method of ectopic expression of transcriptional factors. In an in vitro model for Alzheimer’s disease, kenpaullone decreased production of amyloid beta peptides Aβ40 and Aβ42.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 326.00548
• Fórmula: C₁₆H₁₁BrN₂O
• Pureza: Min. 95%
• Cor/forma: Yellow To Dark Yellow Solid
• InChI: InChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)
• Chave InChI: InChIKey=QQUXFYAWXPMDOE-UHFFFAOYSA-N
• SMILES: O=C1Cc2c([nH]c3ccc(Br)cc23)-c2ccccc2N1