b-Lapachone
CAS: 4707-32-8
Ref. 3D-FL170803
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Informação sobre produto
- 2,2-Dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dione
- 2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene-5,6-dione
- 2H-Naphtho(1,2-b)pyran-5,6-dione, 3,4-dihydro-2,2-dimethyl-
- 3,4-Dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione
- Arq-501
- Brn 0181499
- Lapachone, beta-
- Mb 12066
- Nsc 26326
- Nsc 629749
- Ver mais sinónimos
- Sl 11001
- beta-Lapachone
- β-Lapachone
- 5-17-11-00459 (Beilstein Handbook Reference)
b-Lapachone is a naturally occurring compound that has been shown to be cytotoxic in vitro. It has significant cytotoxicity against HL-60 cells and has been shown to inhibit the activity of enzymes such as cyclin d2, which regulates cell cycle progression, and topoisomerase II, which maintains genomic stability. b-Lapachone also has pro-apoptotic properties, which means it induces programmed cell death (PCD) by activating caspases. This apoptosis can lead to neurodegenerative disorders or brain function changes. Furthermore, b-lapachone has been shown to stimulate mitochondrial functions and polymer compositions, which may have implications for drug delivery systems.
Propriedades químicas
Consulta técnica sobre: 3D-FL170803 b-Lapachone
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