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Linifanib
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Linifanib

CAS: 796967-16-3

Ref. 3D-FL24895

1mgDescontinuado
2mgDescontinuado
5mgDescontinuado
10mgDescontinuado
25mgDescontinuado

Produto descontinuado. Para obter informações sobre produtos semelhantes, preencha o nosso formulário de pedido de informações ou envie-nos uma mensagem de correio eletrónico para support@cymitquimica.com.


Informação sobre produto

Nome:
Linifanib
Sinónimos:
  • N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)ureaABT 869
  • Abt 869
  • Al 39324
  • Linigfanib
  • N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N′-(2-fluoro-5-methylphenyl)urea
  • Rg 3635
  • Urea, N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)-
Descrição:

Linifanib is a cyclic peptide that inhibits the mcl-1 protein, which is involved in the regulation of apoptosis. Linifanib has been shown to inhibit the expression of genes encoding for proteins involved in the signal pathways and angiogenic process, such as VEGF-A and MMP2 respectively. This drug has also been shown to inhibit cancer cell proliferation in vitro and in vivo models. The mechanism of action of linifanib is not yet fully known but it is thought to be due to its ability to induce autophagy or apoptosis. It can be used for the treatment of renal cell cancer and eye disorders such as age-related macular degeneration (AMD).

Aviso:
Os nossos productos estão destinados exclusivamente para uso em laboratório. Para qualquer outra aplicação, por favor entre em contacto.
Marca:
Biosynth
Armazenamento a longo prazo:
Notas:

Propriedades químicas

Peso molecular:
375.4 g/mol
Fórmula:
C21H18FN5O
Pureza:
Min. 95%
InChI:
InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)
Chave InChI:
InChIKey=MPVGZUGXCQEXTM-UHFFFAOYSA-N
SMILES:
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1
MDL:
Ponto de fusão:
Ponto de ebulição:
Ponto de inflamação:
Densidade:
Concentração:
EINECS:
Merck:
Código HS:

Informação sobre riscos

Número ONU:
EQ:
Classe:
Frases H:
Frases P:
Proibido de voar:
Informação sobre riscos:
Grupo de Embalagem:
LQ:

Consulta sobre o produto descontinuado: 3D-FL24895 Linifanib

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