6-Methoxy-1-benzofuran-3(2H)-one

CAS: 15832-09-4

Ref. 3D-FM123798

Informação sobre produto

• Nome: 6-Methoxy-1-benzofuran-3(2H)-one
• Sinónimos: 3(2H)-benzofuranone, 6-methoxy-, 5-Fluoro-3-Benzofuranone, 5-fluoro-1-benzofuran-3(2H)-one

Descrição

6-Methoxy-1-benzofuran-3(2H)-one is a polymerization inhibitor that binds to tubulin and inhibits the polymerization of tubulin. This compound has shown high potency against cancer cells in vitro, including A549 cells, MCF7 cells, and MDA-MB231 cells. 6-Methoxy-1-benzofuran-3(2H)-one also has growth inhibitory activity on cancer cell lines at concentrations of 100 μmol/L or less. This active form is also an aliphatic compound. It can be synthesized from tetrahydrofuran (THF) using various methods such as Noyori coupling or aldol condensation. 6-Methoxy-1-benzofuran-3(2H)-one has been shown to inhibit the growth of cancer cells by binding to the microtubule network and inhibiting the polymerization of tubulin. The mechanism

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 164.16 g/mol
• Fórmula: C₉H₈O₃
• Pureza: Min. 95%
• InChI: InChI=1S/C9H8O3/c1-11-6-2-3-7-8(10)5-12-9(7)4-6/h2-4H,5H2,1H3
• Chave InChI: InChIKey=BLLMRPOVMOPQKC-UHFFFAOYSA-N
• SMILES: COc1ccc2c(c1)OCC2=O