2-(1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid

CAS: 26171-23-3

Ref. 3D-FM140506

Informação sobre produto

• Nome: 2-(1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid
• Sinónimos: 1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid, 1-Methyl-5-(p-toluoyl)-2-pyrroleacetic acid, 1-Methyl-5-p-toluoylpyrrole-2-acetic acid, 1-methyl-5-[(4-methylphenyl)carbonyl]-1H-pyrrole-2-carboxylic acid, 1H-pyrrole-2-acetic acid, 1-methyl-5-(4-methylbenzoyl)-, 2-[1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid, 247-497-2, 5-[(p-Tolyl)carbonyl]-1-methylpyrrole-2-acetic acid, McN 2559, Pyrrole-2-acetic acid, 1-methyl-5-p-toluoyl-, Tolmetine, Tolmetino, [1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid, sodium [1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetate, Tolmetin

Descrição

2-(1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid is a nonsteroidal antiinflammatory drug that belongs to the group of drugs called arylpropionic acids. The drug is used to relieve inflammation and pain. 2-(1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid has been shown in vitro assays to be toxic to epidermal cells and inhibit the production of inflammatory mediators such as prostaglandins and leukotrienes. The drug also inhibits the production of proinflammatory cytokines such as IL6, IL8, and TNFα by activated human monocytes in vitro. It has been shown to have antiinflammatory activity in experimental models for arthritis, colitis, and asthma.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 257.28 g/mol
• Fórmula: C₁₅H₁₅NO₃
• Pureza: Min. 95%
• InChI: InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18)
• Chave InChI: InChIKey=UPSPUYADGBWSHF-UHFFFAOYSA-N
• SMILES: Cc1ccc(C(=O)c2ccc(CC(=O)O)n2C)cc1