6-Methyl-3,4-dihydronaphthalen-1(2H)-one

CAS: 51015-29-3

Ref. 3D-FM142292

Informação sobre produto

• Nome: 6-Methyl-3,4-dihydronaphthalen-1(2H)-one
• Sinónimos: 1(2H)-Naphthalenone, 3,4-dihydro-6-methyl-, 3,4-Dihydro-6-methyl-1(2H)-naphthalenone, 6-Methyl-1-tetralone, 6-Methyl-α-tetralone, 6-methyl-3,4-dihydronaphthalen-1(2H)-one

Descrição

6-Methyl-3,4-dihydronaphthalen-1(2H)-one is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. This compound is an analog of bexarotene, which is used as a cancer chemotherapeutic agent. 6-Methyl-3,4-dihydronaphthalen-1(2H)-one has been shown to inhibit lipid biosynthesis in the liver by interacting with the ligand binding domain of the peroxisome proliferator -activated receptor alpha (PPARα). The NSAID also inhibits the production of prostaglandins that are involved in inflammation and pain. 6-Methyl-3,4-dihydronaphthalen-1(2H)-one binds to PPARα in the ligand binding domain and prevents it from activating transcription.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 160.21 g/mol
• Fórmula: C₁₁H₁₂O
• Pureza: Min. 95%
• InChI: InChI=1S/C11H12O/c1-8-5-6-10-9(7-8)3-2-4-11(10)12/h5-7H,2-4H2,1H3
• Chave InChI: InChIKey=FPOGGJAFMWYNLI-UHFFFAOYSA-N
• SMILES: Cc1ccc2c(c1)CCCC2=O