1-Methyl-3,4-bis(3-indolyl)maleimide
CAS: 113963-68-1
Ref. 3D-FM154017
| 1g | Descontinuado | ||
| 50mg | Descontinuado | ||
| 100mg | Descontinuado | ||
| 250mg | Descontinuado | ||
| 500mg | Descontinuado |
Informação sobre produto
Nome:
1-Methyl-3,4-bis(3-indolyl)maleimide
Sinónimos:
- 1-Methyl-3,4-bis(indol-3-yl)maleimide
- 1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-1-methyl-
- 3,4-Bis(1H-indol-3-yl)-1-methylpyrrole-2,5-dione
- 3,4-di(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione
- Bisindolylmaleimide V
- Methylarcyriarubin
- Methylarcyriarubin A
- N-Methyl-3,4-bis(indol-3-yl)maleimide
- N-Methylbis(indol-3-yl)maleimide
- Ro 31-6045
- Ver mais sinónimos
Descrição:
1-Methyl-3,4-bis(3-indolyl)maleimide (1M3BM) is a chemical compound that has been shown to be an inhibitor of the epidermal growth factor receptor. It binds to the EGF receptor, thereby preventing the binding of EGF and activation of downstream signaling pathways. 1M3BM inhibits the activity of enzymes that synthesize fatty acids in cells, which may lead to decreased fat accumulation in fat cells. This drug also inhibits the activation of toll-like receptors by blocking nuclear factor κB (NFκB). These effects may help to alleviate diabetic neuropathy.
Aviso:
Os nossos productos estão destinados exclusivamente para uso em laboratório. Para qualquer outra aplicação, por favor entre em contacto.
Marca:
Biosynth
Armazenamento a longo prazo:
Notas:
Propriedades químicas
Peso molecular:
341.36 g/mol
Fórmula:
C21H15N3O2
Pureza:
Min. 95%
InChI:
InChI=1S/C21H15N3O2/c1-24-20(25)18(14-10-22-16-8-4-2-6-12(14)16)19(21(24)26)15-11-23-17-9-5-3-7-13(15)17/h2-11,22-23H,1H3
Chave InChI:
InChIKey=SWAWYMIKGOHZMR-UHFFFAOYSA-N
SMILES:
CN1C(=O)C(c2c[nH]c3ccccc23)=C(c2c[nH]c3ccccc23)C1=O
MDL:
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Ponto de ebulição:
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Código HS:
