Murideoxycholic acid

CAS: 668-49-5

Ref. 3D-FM167273

Informação sobre produto

• Nome: Murideoxycholic acid
• Sinónimos: 5?-Cholanic Acid-3?,6?-diol3?,6?-Dihydroxy-5?-cholan-24-oic Acid3?,6?-Dihydroxy-5?-cholanic Acid, (3α,5β,6β)-3,6-Dihydroxycholan-24-oic acid, 3a,6b-Dihydroxy-5b-cholan-24-oic acid, 3α,6β-Dihydroxy-5β-cholanic acid, 3α,6β-Dihydroxy-5β-cholanoic acid, 3α,6β-Dihydroxycholanoic acid, 5β-Cholan-24-oic acid, 3α,6β-dihydroxy-, 5β-Cholanic acid, 3α,6β-dihydroxy-, 668-49-5, 6β-Hydroxylithocholic acid, Cholan-24-oic acid, 3,6-dihydroxy-, (3.alpha.,5.beta.,6.beta.)-, Cholan-24-oic acid, 3,6-dihydroxy-, (3α,5β,6β)-, Murocholic acid, NSC 18166

Descrição

Murideoxycholic acid is a bile acid that is used in combination with other antibiotics to treat infections caused by bacteria. Murideoxycholic acid inhibits the bacterial transport of bile acids, which are important for the digestion of fats and proteins. Murideoxycholic acid binds to the cytochrome P450 enzyme in humans and rats, inhibiting its activity. This binding prevents the production of bile acids from cholesterol in the liver, which prevents their normal excretion into the intestine and leads to an increased risk for gallstones. Murideoxycholic acid also has been shown to inhibit human CYP3A4 enzyme activity. The hydroxyl group on this molecule reacts with ferrous ions to produce hydroxyl radicals, which can lead to oxidative stress and lipid peroxidation.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 392.57 g/mol
• Fórmula: C₂₄H₄₀O₄
• Pureza: Min. 95%