N-4-Methoxyphenylretinamide

CAS: 79965-10-9

Ref. 3D-FM25343

Informação sobre produto

• Nome: N-4-Methoxyphenylretinamide
• Sinónimos: N-(4-Methoxyphenyl)-all-trans-retinamideN-(4-Methoxyphenyl)retinamideN-(p-Methoxyphenyl)retinamide

Descrição

N-4-Methoxyphenylretinamide (4-HPR) is a potent inhibitor of cytochrome P450 enzymes, including CYP3A4. 4-HPR inhibits the activity of fatty acid synthase and mitochondrial membrane depolarization. It has been shown to inhibit the growth of human carcinoma cell lines in vivo. 4-HPR also has anti-inflammatory properties, as it suppresses reactive oxygen species production in human neutrophils. This compound is not specific for any one type of cancer, but does have an effect on T cell lymphomas and women with fatty acid metabolism disorders.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 405.57 g/mol
• Fórmula: C₂₇H₃₅NO₂
• Pureza: Min. 95%
• InChI: InChI=1S/C27H35NO2/c1-20(12-17-25-22(3)11-8-18-27(25,4)5)9-7-10-21(2)19-26(29)28-23-13-15-24(30-6)16-14-23/h7,9-10,12-17,19H,8,11,18H2,1-6H3,(H,28,29)/b10-7+,17-12+,20-9+,21-19+
• Chave InChI: InChIKey=DBQHWMPFMCOGIW-ABRSJASVSA-N
• SMILES: COc1ccc(NC(=O)/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)cc1