3-O-Methyl tolcapone

CAS: 134612-80-9

Ref. 3D-FM25570

Informação sobre produto

• Nome: 3-O-Methyl tolcapone
• Sinónimos: (4-Hydroxy-3-methoxy-5-nitrophenyl)(4-methylphenyl)methanone4-Hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenoneRo 40-7591, 3-O-methyltolcapone, (4-Hydroxy-3-Methoxy-5-Nitrophenyl)(4-Methylphenyl)Methanone
• CAS: 134612-80-9

Descrição

3-O-Methyl tolcapone is a catechol-O-methyltransferase (COMT) inhibitor that is used to treat Parkinson's disease. It has been shown to increase the plasma concentrations of levodopa by about 40% in humans. This drug is also effective for the treatment of Parkinson's disease in animals, and has been shown to be safe for use in humans. 3-O-Methyl tolcapone is given orally as a tablet and it is absorbed from the gastrointestinal tract. The drug binds competitively with COMT, thereby inhibiting its activity. This inhibition leads to increased levels of levodopa and dopamine in the brain, which can improve symptoms of Parkinson's disease.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 287.27 g/mol
• Fórmula: C₁₅H₁₃NO₅
• Pureza: Min. 95%
• Cor/forma: Yellow Powder