(2S,4S)-4-Methylglutamic acid
CAS: 6141-27-1
Ref. 3D-FM25845
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Informação sobre produto
- (4S)-4-Methyl-L-glutamic Acid
(2S,4S)-4-Methylglutamic acid is a synthetic glutamate analog that can bind to the active site of daptomycin. It has been shown to have a higher binding affinity than natural glutamate and is stable at high temperatures. This compound has been evaluated in binding experiments and functional assays against carbapenem-resistant Gram-positive bacteria, including methicillin resistant Staphylococcus aureus (MRSA) and Enterococcus faecium. The synthesis of this compound was achieved by solid-phase synthesis, which used commercially available amino acids. The chemical profile of this analog was also evaluated using various assays, such as uptake assays on retinal neurons. A synthetic scheme was developed for the preparation of this compound.
Propriedades químicas
Consulta técnica sobre: 3D-FM25845 (2S,4S)-4-Methylglutamic acid
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