4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol
CAS: 76014-81-8
Ref. 3D-FM25896
1mg | 136,00 € | ||
5mg | 234,00 € | ||
25mg | 548,00 € | ||
50mg | 820,00 € | ||
100mg | 1.194,00 € |
Informação sobre produto
- a-[3-(Methylnitrosoamino)propyl]-3-pyridinemethanolracNNAL4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)butan-1-ol
- (±)-Nnal
- 3-Pyridinemethanol, Alpha-[3-(Methylnitrosoamino)Propyl]-
- 3-Pyridinemethanol, α-[3-(methylnitrosoamino)propyl]-
- 4-(Methylnitrosoamino)-1--(3-Pyridyl)-1-Butanol
- 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)butan-1-ol
- 4-[Methyl(nitroso)amino]-1-(3-pyridinyl)-1-butanol
- 76014-81-8
- Racemic 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol
- Racemic NNAL
- Ver mais sinónimos
- α-[3-(Methylnitrosoamino)propyl]-3-pyridinemethanol
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is a metabolite of nicotine that has been shown to be carcinogenic in vivo. It binds to DNA, forming adducts with guanine, and can cause mutations and chromosomal aberrations. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol is excreted in urine as a glucuronide conjugate. Its potential use as a biomarker for tobacco smoking has been demonstrated by the observation of increased levels following exposure to cigarette smoke. The urinary concentration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol has been correlated with the risk for lung cancer in humans, and it may be useful as an analytical method for determining tobacco consumption.
Propriedades químicas
Consulta técnica sobre: 3D-FM25896 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol
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