Informação sobre produto
- 4-(Carbomethoxy)iodobenzene
- 4-(Methoxycarbonyl)-1-iodobenzene
- 4-(Methoxycarbonyl)iodobenzene
- 4-(Methoxycarbonyl)phenyl iodide
- 4-Iodobenzoic acid methyl ester
- Benzoic acid, 4-iodo-, methyl ester
- Benzoic acid, p-iodo-, methyl ester
- Methyl p-iodobenzoate
- NSC 9393
- p-(Methoxycarbonyl)phenyl iodide
- Ver mais sinónimos
- p-Iodobenzoic acid methyl ester
Methyl-4-iodobenzoate is an organic compound that can be used as a precursor to the synthesis of pemetrexed, a drug that has been shown to be effective against cancer. Methyl-4-iodobenzoate is synthesized by combining 4-iodobenzoic acid with methyl iodide in the presence of sodium azide. The reaction mechanism is thought to involve the formation of an aziridine intermediate and proceeds via a suzuki coupling reaction. This compound can also be synthesized through hydrolysis of methyltriazole and azetidinium chloride with potassium hydroxide, followed by chlorination with hydrochloric acid. Methyl-4-iodobenzoate is soluble in organic solvents such as chloroform and ether, but not in water.
Propriedades químicas
Consulta técnica sobre: 3D-FM30437 Methyl-4-iodobenzoate
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