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2-Methyl-2-phenoxypropanoic acid
CAS: 943-45-3
Ref. 3D-FM31637
1g | A consultar | ||
2g | A consultar | ||
5g | A consultar | ||
10g | A consultar | ||
500mg | A consultar |
Informação sobre produto
- 2,2-Dimethyl-2-phenoxyacetic acid
- 2,2-Dimethylphenoxyacetic acid
- 2-Methyl-2-Phenoxypropanoic Acid
- 2-Phenoxy-2,2-dimethyl acetic acid
- 2-Phenoxy-2-methylpropionic acid
- 2-Phenoxyisobutyric acid
- Fibric acid
- NSC 34010
- Phenoxy-iso-Butyric acid
- Phenoxy-α-isobutyric acid
- Ver mais sinónimos
- Phenoxyisobutyric acid
- Propanoic acid, 2-methyl-2-phenoxy-
- Propionic acid, 2-methyl-2-phenoxy-
2-Methyl-2-phenoxypropanoic acid is an inhibitor of the enzyme PCSK9. It is a potent and selective inhibitor of PCSK9 with IC50 values in the low nanomolar range. 2-Methyl-2-phenoxypropanoic acid has been shown to decrease hepatic cholesterol levels by inhibiting the activity of PCSK9, which is required for the production of LDL receptors that are responsible for removing LDL from the bloodstream. 2-Methyl-2-phenoxypropanoic acid is orally administered and has a half life of about 6 hours. This drug may be used to treat hypercholesterolemia, metabolic disorders, or genetic conditions such as familial hypercholesterolemia. The mechanism of action of 2methyl 2 phenoxypropanoic acid involves its inhibition of hepatic lipases, leading to increased uptake and reduced catabolism of LDL cholesterol particles in hepatocytes. It also inhibits transcriptional regulation by interacting with
Propriedades químicas
Consulta técnica sobre: 3D-FM31637 2-Methyl-2-phenoxypropanoic acid
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