Cobicistat

CAS: 1004316-88-4

Ref. 3D-FM40808

Informação sobre produto

• Nome: Cobicistat
• Sinónimos: (3R,6R,9S)-2-Methyl-13-[2-(1-methylethyl)-4-thiazolyl]-9-[2-(4-morpholin yl)ethyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic acid 5-thiazolylmethyl esterTybostGS-9350

Descrição

Cobicistat is an inhibitor of human cytochrome P450 3A enzymes (CYP) with no antiviral activity. Cobicistat is used in the treatment of HIV-1 infection, as an alternative to ritonavir, to increase the half-life of antiviral medications (von Hentig, 2016). Cobicistat acts as a booster by selectively inhibiting the hepatic degradation of the drugs, for example, in the pharmacological regime against HIV-1, which often includes protease inhibitors, such as, darunavir, atazanavir, and lopinavir, or the integrase inhibitor elvitegravir (Deeks, 2014).

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 776.03 g/mol
• Fórmula: C₄₀H₅₃N₇O₅S₂
• Pureza: Min. 95%
• Cor/forma: Powder