trans-3-(4-Methylbenzoyl)acrylic acid

CAS: 20972-36-5

Ref. 3D-FM54337

Informação sobre produto

• Nome: trans-3-(4-Methylbenzoyl)acrylic acid
• Sinónimos: 4-(4-Methylphenyl)-4-oxobut-2-enoic acid, 3-(4-Methylbenzoyl)acrylic acid, (2E)-4-(4-methylphenyl)-4-oxobut-2-enoic acid

Descrição

The compound trans-3-(4-methylbenzoyl)acrylic acid is a potent and selective inhibitor of serine/threonine protein kinase. It has been shown to inhibit the proliferation of eosinophils in vitro, as well as to suppress the release of leukotrienes from human mast cells. The mechanism of action is by inhibiting phosphatidylcholine-specific phospholipase C, which leads to the inhibition of protein kinase C. This inhibition prevents the phosphorylation of various proteins, including cytoskeletal proteins that are required for cell division.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 190.2 g/mol
• Fórmula: C₁₁H₁₀O₃
• Pureza: Min. 95%
• InChI: InChI=1S/C11H10O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h2-7H,1H3,(H,13,14)/b7-6+
• Chave InChI: InChIKey=VNJMEFZKYZHWEO-VOTSOKGWSA-N
• SMILES: Cc1ccc(C(=O)/C=C/C(=O)O)cc1