17alpha-Methyl-19-nortestosterone

CAS: 514-61-4

Ref. 3D-FM66032

Informação sobre produto

• Nome: 17alpha-Methyl-19-nortestosterone
• Sinónimos: 4-Estren-17alpha-methyl-17beta-ol-3-oneNormethandrone(17b)-Hydroxy-17-a-methyloestr-4-en-3-oneMethylestrenolone, (17Beta)-17-Hydroxy-17-Methylestr-4-En-3-One, (17β)-17-Hydroxy-17-methylestr-4-en-3-one, 13β,17α-Dimethyl-17-hydroxygon-4-en-3-one, 17-Hydroxy-17-Methylestr-4-En-3-One, 17-Methyl-19-nortestosterone, 17α-Methyl-17β-hydroxy-4-estrene-3-one, 17α-Methyl-17β-hydroxy-Δ⁴-estren-3-one, 17α-Methyl-19-nortestosterone, 17α-Methyl-3-oxo-4-estren-17β-ol, 17α-Methyl-4-estren-17β-ol-3-one, 17α-Methylestra-4-en-17-ol-3-one, 17α-Methylestrenolone, 17β-Hydroxy-17-methylestr-4-en-3-one, 17β-Hydroxy-17α-methylestr-4-en-3-one, 19-Normethisterone, Estr-4-en-3-one, 17-hydroxy-17-methyl-, (17β)-, Estr-4-en-3-one, 17β-hydroxy-17-methyl-, Lutenin, Matronal, Metalutin, Methalutin, Methylestrenolone, Methylnortestosterone, Methyloestrenolone, NSC 10039, Normetandrone, Normethandrolone, Normethandrone, Normethanedrolone, Normethisterone, Orgasteron, Ru 598

Descrição

17alpha-Methyl-19-nortestosterone (17MT) is an anti-cancer agent that has been used as a contraceptive. It inhibits the conversion of testosterone to dihydrotestosterone by competitive inhibition of the enzyme 3beta-hydroxysteroid dehydrogenase, which is responsible for the first step in the biosynthesis of androgens. 17MT has also been shown to inhibit angiotensin II formation, thereby reducing blood pressure. This drug acts as a structural analogue of progesterone and binds to progesterone receptors, as well as other steroid receptors, with high affinity. 17MT also inhibits fatty acid synthesis in cancer cells, leading to decreased tumor growth.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 288.42 g/mol
• Fórmula: C₁₉H₂₈O₂
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C19H28O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h11,14-17,21H,3-10H2,1-2H3/t14-,15+,16+,17-,18-,19-/m0/s1
• Chave InChI: InChIKey=ZXSWTMLNIIZPET-ZOFHRBRSSA-N
• SMILES: C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@@]21C