Methyl 3,5-dibromo-4-hydroxybenzoate

CAS: 41727-47-3

Ref. 3D-FM70987

Informação sobre produto

• Nome: Methyl 3,5-dibromo-4-hydroxybenzoate
• Sinónimos: Benzoic acid, 3,5-dibromo-4-hydroxy-, methyl ester, 3,5-Dibromo-4-hydroxybenzoic acid methyl ester

Descrição

Estrogens are steroid hormones that regulate a variety of physiological processes including reproduction, bone metabolism, and the development of certain cancers. Estrogens are synthesized from C-19 and C-20 steroids such as progesterone and testosterone. The conversion of these precursors to estrogens is catalyzed by the cytochrome P450 enzyme 17 beta-hydroxysteroid dehydrogenase (17βHSD). Methyl 3,5-dibromo-4-hydroxybenzoate is a selective inhibitor for 17βHSD. It binds to the active site of 17βHSD, preventing it from catalyzing the conversion of C-19 or C-20 steroids to estrogens. This inhibition has been shown to lead to an increase in circulating levels of sex hormone binding globulin (SHBG) and consequently a decrease in free estrogen levels.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 309.94 g/mol
• Fórmula: C₈H₆Br₂O₃
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C8H6Br2O3/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,11H,1H3
• Chave InChI: InChIKey=NVGJGYZKXBLIKY-UHFFFAOYSA-N
• SMILES: COC(=O)c1cc(Br)c(O)c(Br)c1