2-(4-Methoxyphenyl)benzothiazole

CAS: 6265-92-5

Ref. 3D-FM75874

Informação sobre produto

• Nome: 2-(4-Methoxyphenyl)benzothiazole
• Sinónimos: 2-(4-Methoxy-phenyl)-benzothiazole, 2-(4-Methoxyphenyl)Benzothiazole, 2-(4-Methoxyphenyl)benzo[d]thiazole, 2-(p-Methoxyphenyl)benzothiazole, Benzothiazole, 2-(4-methoxyphenyl)-, Benzothiazole, 2-(p-methoxyphenyl)-, NSC 33161

Descrição

2-(4-Methoxyphenyl)benzothiazole is a hydrogen-bond acceptor that is activated in the presence of an electron-withdrawing group. It has been shown to have anti-fungal properties and inhibitory properties against bacteria. 2-(4-Methoxyphenyl)benzothiazole also inhibits the activity of topoisomerase, which is an enzyme that controls DNA supercoiling and uncoiling, as well as DNA replication. The mechanism of this inhibition is not known, but it is thought to be due to the ability of 2-(4-methoxyphenyl)benzothiazole to form hydrogen bonds with the active site cysteine residues on topoisomerase I. 2-(4-Methoxyphenyl)benzothiazole also has been shown to be photophysical in nature, absorbing light at wavelengths of 350 nm and 480 nm and emitting light

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 241.31 g/mol
• Fórmula: C₁₄H₁₁NOS
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C14H11NOS/c1-16-11-8-6-10(7-9-11)14-15-12-4-2-3-5-13(12)17-14/h2-9H,1H3
• Chave InChI: InChIKey=AOPZIJQISHFZBN-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2nc3ccccc3s2)cc1