5-Nitro nicotinic acid

CAS: 2047-49-6

Ref. 3D-FN26238

Informação sobre produto

• Nome: 5-Nitro nicotinic acid
• Sinónimos: 5-Nitro-3-pyridinecarboxylic acid3-Carboxy-5-nitropyridine, 3-Pyridinecarboxylic Acid, 5-Nitro-, 5-Nitropyridine-3-Carboxylic Acid

Descrição

5-Nitro nicotinic acid is a drug that has been synthesized in the laboratory. It is a white crystalline solid with a molecular weight of 201.18, and it has the chemical formula of C6H5NO2. 5-Nitro nicotinic acid is an antitubercular drug that inhibits Mycobacterium tuberculosis and Mycobacterium avium complex without inhibiting other human cells. It also inhibits the growth of bacteria that are resistant to aminoglycosides (e.g., Pbtz169). This drug binds to the enzyme NADH dehydrogenase, which leads to inhibition of bacterial respiration and ATP synthesis. 5-Nitro nicotinic acid also has antimycobacterial activity against mycobacteria by forming nitric oxide radicals (NO) through hydrogen peroxide oxidation, which react with cellular components such as DNA and proteins.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 168.11 g/mol
• Fórmula: C₆H₄N₂O₄
• Pureza: Min. 95%