N-Nitroso guvacoline

CAS: 55557-02-3

Ref. 3D-FN26351

Informação sobre produto

• Nome: N-Nitroso guvacoline
• Sinónimos: 1,2,5,6-Tetrahydro-1-nitroso-3-pyridinecarboxylic acid methyl esterNitrosoguvacoline, 1-Nitroso-1,2,5,6-tetrahydronicotinic acid methyl ester, 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-nitroso-, methyl ester, Brn 0391077, Ccris 3050, Methyl 1-Nitroso-1,2,5,6-Tetrahydropyridine-3-Carboxylate, N-Nitrosoguvacine, Nicotinic acid, 1,2,5,6-tetrahydro-1-nitroso-, methyl ester, Nitrosoguvacoline

Descrição

N-Nitroso guvacoline is a nitrosated guvacoline analog that is used to induce cancer in animals and as an experimental tool for studying the role of acetylcholine in lung cancer. N-Nitroso guvacoline has been shown to inhibit the growth of bacteria such as typhimurium and nadph-cytochrome p450 in the presence of fatty acids, suggesting that it may be genotoxic. The carcinogenic effects of N-nitrosoguvacolin were studied using Sprague-Dawley rats exposed to this agent by inhalation. The rats were found to have increased levels of urinary nitrite and nitrate, which are products from the metabolism of N-nitrosoguvacolin.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 170.17 g/mol
• Fórmula: C₇H₁₀N₂O₃
• Pureza: Min. 95%
• InChI: InChI=1S/C7H10N2O3/c1-12-7(10)6-3-2-4-9(5-6)8-11/h3H,2,4-5H2,1H3
• Chave InChI: InChIKey=NXEUEKXJAAVKCT-UHFFFAOYSA-N
• SMILES: COC(=O)C1=CCCN(N=O)C1