1-(1-Naphthylmethyl)piperazine

CAS: 40675-81-8

Ref. 3D-FN66365

Informação sobre produto

• Nome: 1-(1-Naphthylmethyl)piperazine
• Sinónimos: 1-(1-naphthylmethyl)piperazine

Descrição

1-(1-Naphthylmethyl)piperazine (1-NMPP) is an antimicrobial agent that inhibits bacterial efflux pumps. It was shown to be active against Gram-positive bacteria, such as Erythromycin and tetracycline resistant mutants. 1-NMPP has been shown to inhibit the expression of efflux pump proteins in Gram-negative bacteria. One study showed that 1-NMPP can reverse the resistance of colistin and sulfa drugs in a multidrug resistant strain of Staphylococcus aureus. The mechanism of action for this drug is not yet known, but it may be due to its ability to prevent the synthesis of new efflux pump proteins by inhibiting translation or by decreasing mRNA stability.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 226.32 g/mol
• Fórmula: C₁₅H₁₈N₂
• Pureza: Min. 95%
• Cor/forma: Off-White Powder