2-Nitro-3,4,5-trimethoxybenzoic acid

CAS: 66907-52-6

Ref. 3D-FN70167

Informação sobre produto

• Nome: 2-Nitro-3,4,5-trimethoxybenzoic acid
• Sinónimos: 3,4,5-Trimethoxy-2-Nitrobenzoate, Benzoic acid, 3,4,5-trimethoxy-2-nitro-, NSC 100936

Descrição

2-Nitro-3,4,5-trimethoxybenzoic acid (2-NTMB) is a potent anticancer agent that has shown cytotoxic effects in human epidermoid carcinoma cells. It inhibits the growth of cancer cells by interfering with their DNA synthesis and repair. 2-NTMB binds to DNA and blocks the action of enzymes involved in DNA synthesis and repair. This binding leads to cancer cell death through irradiation or by blocking the production of new proteins vital for cell division. 2-NTMB is bioisosteric with combretastatin A4, which means it can be substituted for this drug without significant loss of potency. It also has been shown to be an effective chemotherapeutic agent against breast cancer in mice.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 257.2 g/mol
• Fórmula: C₁₀H₁₁NO₇
• Pureza: Min. 95%
• Cor/forma: Powder