OSU-03012,Hydrochloride Salt

CAS: 742112-33-0

Ref. 3D-FO29768

Informação sobre produto

• Nome: OSU-03012,Hydrochloride Salt
• Sinónimos: 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide, 2-Amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide, AR 12 (pharmaceutical), Acetamide, 2-amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-, Ar-12, Osu-03012
• CAS: 742112-33-0

Descrição

OSU-03012 is a broad-spectrum antimicrobial with a novel mechanism of action. It inhibits the pyrazole ring and blocks the synthesis of nucleic acids, which prevents cell proliferation and induces apoptosis. OSU-03012 has been shown to be active against bacteria such as Streptococcus pneumoniae, methicillin-resistant Staphylococcus aureus (MRSA), Mycobacterium tuberculosis, and Chlamydia trachomatis; fungi such as Candida albicans; viruses such as herpes simplex virus type 1 (HSV-1) and human immunodeficiency virus type 1 (HIV-1); and protozoa such as Entamoeba histolytica. In addition, OSU-03012 does not induce resistance in viruses or bacteria, suggesting that it may have use for long periods of time. The chemical structure of OSU-03012 has been elucidated using nuclear magnetic resonance

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 460.45 g/mol
• Fórmula: C₂₆H₁₉F₃N₄O
• Pureza: Min. 95%
• InChI: InChI=1S/C26H19F3N4O/c27-26(28,29)24-14-23(33(32-24)20-10-8-19(9-11-20)31-25(34)15-30)18-7-12-22-17(13-18)6-5-16-3-1-2-4-21(16)22/h1-14H,15,30H2,(H,31,34)
• Chave InChI: InChIKey=YULUCECVQOCQFQ-UHFFFAOYSA-N
• SMILES: NCC(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2-c2ccc3c(ccc4ccccc43)c2)cc1