3,4-Pyridine dicarboxylic acid
CAS: 490-11-9
Ref. 3D-FP01987
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Informação sobre produto
- 3,4-Pyridine Dicarboxylic Acid
- Chinchomeronic acid
- Cinchomeronic Acid Crystalline
- Cinchomeronic acid
- NSC 178
- Pyridine-3,4-Dicarboxylate
- Pyridine-3,4-dicarboxylic acid
3,4-Pyridine dicarboxylic acid is a sodium salt of pyridine-dicarboxylic acid. It has been shown to inhibit the growth of HL-60 cells by binding with copper and inhibiting the activity of 3-hydroxyanthranilic acid in the electron transfer chain. This inhibits cellular respiration and ATP production, which leads to cell death. 3,4-Pyridine dicarboxylic acid binds to picolinic acid by hydrogen bonding interactions and coordinates with copper ions through a geometry that is not ideal for either molecule. This coordination prevents protonation of the carboxylate group on picolinic acid, which disrupts its catalytic activity.
Propriedades químicas
Consulta técnica sobre: 3D-FP01987 3,4-Pyridine dicarboxylic acid
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