Phenylmethyl N-[(2S)-1-Oxo-1-[[(2S)-1-Oxo-1-[[(2S)-1-(1,1,1-Trifluoro-4-Methyl-2-Oxopentan-3-Yl)Pyrrolidine-2-Carbonyl]Amino]Propan- 2-Yl]Amino]Propan-2-Yl]Carbamate
CAS: 110407-54-0
Ref. 3D-FP104223
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Informação sobre produto
- Caapv
- Cbz-ala-ala-pro-ambo-val-CF3
- L-Prolinamide, N-((phenylmethoxy)carbonyl)-L-alanyl-L-alanyl-N-(2-methyl-1-(trifluoroacetyl)propyl)-
- N-[(benzyloxy)carbonyl]-L-alanyl-N-({(2S)-1-[3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl]pyrrolidin-2-yl}carbonyl)-L-alaninamide
Phenylmethyl N-[(2S)-1-Oxo-1-[[(2S)-1-Oxo-1-[[(2S)-1-(1,1,1-Trifluoro-4-Methyl-2-Oxopentan-3-Yl)Pyrrolidine-2-Carbonyl]Amino]Propan- 2-Yl]Amino]Propan-2-Yl]Carbamate (PMOAC) is a serine proteinase inhibitor that is used to treat inflammatory diseases. It inhibits leukocyte elastase, an enzyme that destroys the elastic fibers in the lungs and other tissues. It has been shown that PMOAC inhibits human leukocyte elastase (HLE) and serine proteases in vitro with IC50 values of 0.6 μM and 0.8 μM, respectively. The inhibitory effect on HLE was found
Propriedades químicas
Consulta técnica sobre: 3D-FP104223 Phenylmethyl N-[(2S)-1-Oxo-1-[[(2S)-1-Oxo-1-[[(2S)-1-(1,1,1-Trifluoro-4-Methyl-2-Oxopentan-3-Yl)Pyrrolidine-2-Carbonyl]Amino]Propan- 2-Yl]Amino]Propan-2-Yl]Carbamate
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