PAR-2 (1-6) amide (human) trifluoroacetate salt

CAS: 190383-13-2

Ref. 3D-FP109317

Informação sobre produto

• Nome: PAR-2 (1-6) amide (human) trifluoroacetate salt
• Sinónimos: H-Ser-Leu-Ile-Gly-Lys-Val-NH2 H-SLIGKV-NH2, Protease-Activated Receptor-2 Agonist, Amide, Proteinase Activated Receptor 2 (1-6) Amide (Human), Proteinase Activated Receptor 2 Agonist Peptide Sligkv Amide, Human, Ser-Leu-Ile-Gly-Lys-Val-Amide, Ser-Leu-Ile-Gly-Lys-Val-Nh2, Sligkvamide, Sligkv-Nh2, Par-2 Agonist Peptide (Sligkv) Amide, Human

Descrição

PAR-2 (1-6) amide (human) trifluoroacetate salt H-Ser-Leu-Ile-Gly-Lys-Val-NH2 trifluoroacetate salt is a protease inhibitor that inhibits the activity of PAR2, a protein receptor. PAR2 is implicated in cancer and inflammation. It has been shown to inhibit growth factor signaling, as well as activate toll-like receptor 4 and other inflammatory pathways. PAR2 inhibition has also been studied in vivo and found to be effective in treating wild type mice with melanoma cells. In vitro studies have shown that PAR2 inhibition by PAR 2 (1-6) amide (human) trifluoroacetate salt H-Ser-Leu-Ile-Gly-Lys-Val NH2 trifluoroacetate salt blocks the production of tumour necrosis factor alpha and interleukin 6.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 614.78 g/mol
• Fórmula: C₂₈H₅₄N₈O₇
• Pureza: Min. 95%