PAR-2 (1-6) (human) trifluoroacetate salt

CAS: 202933-49-1

Ref. 3D-FP109441

Informação sobre produto

• Nome: PAR-2 (1-6) (human) trifluoroacetate salt
• Sinónimos: H-Ser-Leu-Ile-Gly-Lys-Val-OH H-SLIGKV-OH

Descrição

PAR-2 is a cytosolic protein that is activated by calcium. PAR-2 activation induces the synthesis of prostaglandins and other inflammatory mediators, which stimulate the release of substances from cells such as cytokines and chemokines. PAR-2 also has an important role in cell proliferation, differentiation, apoptosis, and cancer development. PAR-2 activation is induced by proteases such as trypsin or soybean trypsin inhibitor. The trifluoroacetate salt form of PAR-2 (1-6) has been used to inhibit protease activity in colon cancer cells and prostate cancer cells.
PAR-2 (1-6) (human) trifluoroacetate salt H-Ser-Leu-Ile-Gly-Lys-Val-OH trifluoroacetate salt is a potent chemical inhibitor of trypsin activity with IC50 values of 0.5 µM for soybean trypsin inhibitor

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 615.76 g/mol
• Fórmula: C₂₈H₅₃N₇O₈
• Pureza: Min. 95%