Pancreastatin (33-48) (human) trifluoroacetate salt

CAS: 133605-57-9

Ref. 3D-FP109859

Informação sobre produto

• Nome: Pancreastatin (33-48) (human) trifluoroacetate salt
• Sinónimos: H-Glu-Glu-Glu-Glu-Glu-Met-Ala-Val-Val-Pro-Gln-Gly-Leu-Phe-Arg-Gly-NH2 H-EEEEEMAVVPQGLFRG-NH2
• Marca: Biosynth
• Descrição: Pancreastatin (33-48) is a synthetic, acidic, sulfated peptide that has been shown to have high activity against pancreatic cancer cells. Pancreastatin (33-48) has been synthesized by reacting an oligopeptide with glutamic acid and aspartic acid. The N-terminal of this peptide is amidated and contains a sulfate group. This molecule has been purified by SDS-polyacrylamide gel electrophoresis and the sulfate fractionation method. Pancreastatin (33-48) is able to inhibit the proliferation of pancreatic tumor cells in vitro, but it does not appear to be cytotoxic to normal pancreatic cells. In addition, pancreastatin (33-48) has also been shown to decrease tumor growth in vivo in mice bearing a transplanted human pancreatic tumor.

Propriedades químicas

• Peso molecular: 1,819 g/mol
• Fórmula: C₇₈H₁₂₃N₂₁O₂₇S
• Pureza: Min. 95%