Z-Phe-His-Leu-OH

CAS: 28458-19-7

Ref. 3D-FP110845

Informação sobre produto

• Nome: Z-Phe-His-Leu-OH
• Sinónimos: 2-[[2-[(2-benzyloxycarbonylamino-3-phenyl-propanoyl)amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-4-methyl-pentanoic acid
• CAS: 28458-19-7

Descrição

Z-Phe-His-Leu-OH is a monoclonal antibody that is used in the diagnosis and treatment of prostate cancer. This drug binds to the extracellular domain of the human prostate epithelial cell antigen (PSA), which is overexpressed in prostate cancers. Z-Phe-His-Leu-OH can be used in combination with other drugs for the treatment of prostate hyperplasia, such as angiotensin II receptor antagonists or 5α reductase inhibitors. The conformational epitope of this antibody has been demonstrated by immunohistochemical analysis on human tissues.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 549.62 g/mol
• Fórmula: C₂₉H₃₅N₅O₆
• Pureza: Min. 95%
• InChI: InChI=1S/C29H35N5O6/c1-19(2)13-25(28(37)38)33-27(36)24(15-22-16-30-18-31-22)32-26(35)23(14-20-9-5-3-6-10-20)34-29(39)40-17-21-11-7-4-8-12-21/h3-12,16,18-19,23-25H,13-15,17H2,1-2H3,(H,30,31)(H,32,35)(H,33,36)(H,34,39)(H,37,38)/t23-,24-,25-/m0/s1
• Chave InChI: InChIKey=BOMYCHBQXOKSLT-SDHOMARFSA-N
• SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)O