4-Phenyl-1,2,5-oxadiazol-3-amine
CAS: 1905-75-5
Ref. 3D-FP120341
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Informação sobre produto
- 1,2,5-oxadiazol-3-amine
- 4-phenyl-
- 1,3,4-Oxadiazol-2-Amine, 5-Phenyl-, Hydrochloride (1:1)
- 5-Phenyl-1,3,4-oxadiazol-2-amine hydrochloride (1:1)
4-Phenyl-1,2,5-oxadiazol-3-amine is a benzene derivative that has been used as an analogue of histamine. It is also a histamine receptor antagonist. It has been shown to inhibit the activity of the h2-receptor in rodents and guinea pigs and can be used to extrapolate the effects of histamine on tissues. 4-Phenyl-1,2,5-oxadiazol-3-amine is a competitive inhibitor of the H2 receptor which inhibits the function of this protein by binding to it with higher affinity than histamine. The molecule then blocks the activation or deactivation of G proteins by histamine at this site. This compound has also been shown to have antihistaminergic activities in guinea pig ileum and rat uterus, but does not have any significant effects on muscarinic receptors in these tissues.
Propriedades químicas
Consulta técnica sobre: 3D-FP120341 4-Phenyl-1,2,5-oxadiazol-3-amine
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