2-Phenyl-1,3-oxazole-4-carbonyl chloride

CAS: 1204-70-2

Ref. 3D-FP135939

Informação sobre produto

• Nome: 2-Phenyl-1,3-oxazole-4-carbonyl chloride
• Sinónimos: 4-oxazolecarbonyl chloride, 2-phenyl-

Descrição

2-Phenyl-1,3-oxazole-4-carbonyl chloride (2POCl) is a benzene derivative that has been shown to have an inhibitory effect on TNF-α. 2POCl has been shown to inhibit the catalytic activity of TNFA and can be used as a lead compound for the development of new anti-inflammatory drugs. The molecular modeling studies have shown that 2POCl binds to the active site of TNFA, where it forms a covalent bond with the hydrazide residue. This binding prevents the formation of the reactive intermediate, which leads to inhibition of TNFA activity.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 207.61 g/mol
• Fórmula: C₁₀H₆ClNO₂
• Pureza: Min. 95%
• InChI: InChI=1S/C10H6ClNO2/c11-9(13)8-6-14-10(12-8)7-4-2-1-3-5-7/h1-6H
• Chave InChI: InChIKey=YQNBLEXRJFCKSW-UHFFFAOYSA-N
• SMILES: O=C(Cl)c1coc(-c2ccccc2)n1