γ-Polyglutamic acid sodium - MW > 750,000
CAS: 208106-41-6
Ref. 3D-FP162072
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| 5mg | A consultar | ||
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Informação sobre produto
- gamma-PGAPoly-gamma-L-glutamic acid sodium salt
- Sodium poly(γ-L-glutamate)
- Poly-γ-L-glutamic acid sodium salt
- Poly[imino(1-carboxy-4-oxo-1,4-butanediyl)], sodium salt, (S)-
- Sodium poly(γ-L-glutamate), sru
- Poly[imino[(1S)-1-carboxy-4-oxo-1,4-butanediyl]], sodium salt
Polyglutamic acid is a polymer of gamma-aminobutyric acid (GABA). The sodium salt of this polymer is used as an adjuvant in the treatment of cancer. The sodium salt also has been shown to be effective against infectious diseases, such as tuberculosis and malaria. Polyglutamic acid sodium can act on tumor cells by inhibiting the production of tumor necrosis factor-alpha (TNF-α) and other inflammatory cytokines. In addition, it has been shown to enhance viral transfection in vitro. Gamma-polyglutamic acid sodium has low bioavailability due to poor absorption from the gastrointestinal tract and limited stability in blood plasma. This drug binds to basic fibroblast cells through hydrogen bonds and stimulates cell growth.
Propriedades químicas
Consulta técnica sobre: 3D-FP162072 γ-Polyglutamic acid sodium - MW > 750,000
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