Informação sobre produto
- 1,1'-Biphenyl, 2,3',4,4',5-Pentachloro-
- 1,1′-Biphenyl, 2,3′,4,4′,5-pentachloro-
- 2,3',4,4',5-Pcb
- 2,3',4,4',5-Pentachloro-1,1'-biphenyl
- 2,3′,4,4′,5-PeCB
- 2,3′,4,4′,5-Pentachloro-1,1′-biphenyl
- 2,3′,4,4′,5-Pentachlorobiphenyl
- 2,4,5,3',4'-Pentachlorobiphenyl
- 2,4,5,3′,4′-Pentachlorobiphenyl
- 3,4,2',4',5'-Pentachlorobiphenyl
- Ver mais sinónimos
- 3,4,2′,4′,5′-Pentachlorobiphenyl
- Biphenyl, 2,3',4,4',5-pentachloro-
- Biphenyl, 2,3′,4,4′,5-pentachloro-
- Cb 118
- Cde-99
- Pcb 118
2,3’,4,4’,5-Pentachlorobiphenyl (PCB) is a chlorinated biphenyl that has been shown to cause neurotoxicity in animal studies. PCB was administered to Sprague-Dawley rats at a dose of 2 mg/kg/day for 28 days. The treated group showed decreased locomotor activity and increased brain intracellular calcium concentration. This chemical also causes carcinogenesis in animals, but does not appear to be carcinogenic in humans. Chronic exposure of animals to this chemical has been shown to induce autophagy and changes in the expression of genes related to cellular stress and xenobiotic metabolism.
Propriedades químicas
Consulta técnica sobre: 3D-FP170763 2,3’,4,4’,5-Pentachlorobiphenyl
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