Informação sobre produto
- Aminate base
- Amino guanidine
- Aminoguanidin
- Aminoguanidina
- Aminoguanidine
- Carbamimidic acid, hydrazide
- Carbonohydrazonic Diamide
- Guanidine, amino-
- Guanylhydrazine
- Hydrazinecarboximidamide
- Ver mais sinónimos
- Monoaminoguanidine
Pimagedine is a drug that belongs to the class of drugs called GSH-Px inhibitors. It is used as an experimental drug for the treatment of diabetes. Pimagedine has been shown to have a hypoglycemic effect in an experimental model for diabetes. It also inhibits the activity of aminoguanidine, which leads to an increase in blood sugar levels. The enzyme activities in diabetic animals are inhibited by pimagedine, and this inhibition may be due to its anti-inflammatory properties. Pimagedine has been shown to have protective effects against tubulointerstitial injury and neuronal death in animal models with diabetes.