Plinabulin
CAS: 714272-27-2
Ref. 3D-FP179112
| 1g | Descontinuado | ||
| 2g | Descontinuado | ||
| 5g | Descontinuado | ||
| 250mg | Descontinuado | ||
| 500mg | Descontinuado |
Informação sobre produto
Nome:
Plinabulin
Sinónimos:
- (3Z,6Z)-3-[(5-tert-Butyl-1H-imidazol-4-yl)methylene]-6-(phenylmethylene)-2,5-piperazinedione
- (3Z,6Z)-3-[[5-(1,1-Dimethylethyl)-1H-imidazol-4-yl]methylene]-6-(phenylmethylene)-2,5-piperazinedione
- 2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene]-6-(phenylmethylene)-, (3Z,6Z)-
- Bpi 2358
- Npi 2358
Descrição:
Plinabulin is a drug that inhibits the progress of cancer by inhibiting angiogenesis. Plinabulin binds to a platinum-based chemotherapy called cisplatin and prevents its release into the body, thus inhibiting its cytotoxicity. Plinabulin also has anti-angiogenic effects, which are due to its ability to inhibit the activation of cell signaling pathways, such as those mediated by colony-stimulating factor. Plinabulin's cytotoxicity has been demonstrated in vivo using a skin cancer model, where it showed significant cytotoxicity against tumor cells without affecting nearby healthy cells. This drug also has structural biology implications because it binds with high affinity to human macrophages and can be used for chemical biology studies.
Aviso:
Os nossos productos estão destinados exclusivamente para uso em laboratório. Para qualquer outra aplicação, por favor entre em contacto.
Marca:
Biosynth
Armazenamento a longo prazo:
Notas:
Propriedades químicas
Peso molecular:
336.4 g/mol
Fórmula:
C19H20N4O2
Pureza:
Min. 95%
MDL:
Ponto de fusão:
Ponto de ebulição:
Ponto de inflamação:
Densidade:
Concentração:
EINECS:
Merck:
Código HS:
